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Cholesterol Lowering

Our cholesterol lowering Heart Health medications are used to lower high blood levels of cholesterol (hypercholesterolaemia) and triglycerides to reduce risk of atherosclerosis and cardiovascular disease.

Use the search feature to quickly find the product you are looking for, by entering either the active ingredient, e.g. atorvastatin, or the product name, e.g. Atorlip.

What is cholesterol?

Cholesterol is an insoluble fatty substance that is needed by the body for many functions, such as building cell membranes, producing certain hormones and transporting fat soluble vitamins around the body. It is made in the liver and also obtained from the diet. Cholesterol is transported in the blood along with triglycerides, which is another type of fat. Since cholesterol is not soluble in blood it is carried to and from the liver by lipoproteins. These include low density lipoproteins (LDL) known as “bad” cholesterol because they carry cholesterol from the liver and deposit excess in the arteries. High density lipoproteins (HDL) carry cholesterol back to the liver and are therefore called “good” cholesterol.

High cholesterol and atherosclerosis

If there is more cholesterol in the blood than the body needs, it becomes deposited in the artery walls where it can build up, blocking the arteries and causing hardened areas called plaques, which increases risk of heart disease. This condition is known as atherosclerosis. High cholesterol in the blood and other fats (triglycerides) is known as hypercholesterolaemia and this condition is usually due to lifestyle, including high-fat diet, obesity and lack of exercise, but it can be inherited. The ratio of total cholesterol over HDL (good cholesterol) is also an important consideration.

Cholesterol lowering medications

Cholesterol lowering medications are available to treat hypercholesterolaemia in people who have not responded to a low-fat diet and lifestyle changes alone; also for those with an inherited condition and who cannot lower cholesterol levels by lifestyle changes alone. They include:
  • Statins that block the production of cholesterol by the liver, by inhibiting the action of the enzyme HMG-CoA reductase that plays an important role in cholesterol synthesis. Statins only block cholesterol produced in the liver but have no effect on cholesterol that comes from fat in the diet. Several statins are available including, atorvastatin, simvastatin, pravastatin and rosuvastatin.

  • Cholesterol absorption inhibitors, like ezetimibe act directly on the small intestine wall to block the action of the sterol transporter in the intestine wall. This action inhibits intestinal absorption of cholesterol from the diet and reduces cholesterol stores in the liver, which helps lower blood cholesterol levels.

  • Fibrates like fenofibrate activate the enzyme Peroxisome Proliferator Activated Receptor type alpha (PPARα) that regulates the production of another enzyme involved in the breakdown of lipids in the blood. It also reduces the production of proteins that transport LDL lipids but increases the production of proteins that transport HDL. The overall effect is to lower triglycerides, total cholesterol, and LDL (bad) cholesterol, and increase HDL (good) cholesterol.

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Testimonials

Hear from more than 1000 happy customers!
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"This company is excellent. The customer service is second to none. They are helpful and always willing to help in anyway they can. Medications are safe and sent promptly. Would recommend using them without any hesitation. "
PAUL UK • October 2021
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"Thank you for your amazing product line, service, convenience, and security!"
Catherine CA, USA • February 2020
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"You guys are great keep doing what you're doing, i'd give y'all a tip if there was an option"
Stevie Rhodes UK • May 2025
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"There's never been any problem, and the meds I purchased have saved my life. You are a blessing. Thank you so much."
Alberto UK • October 2020
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""Very helpful. Swift reply to any queries and nicely packaged items.""
Michelle London, UK • February 2021
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"Thank You for the Professional and Prompt way you have handled my missing shipment.  I have been doing business with you for a long time and I so much appreciate when a company values their customers and addresses issues in such a caring way and with such integrity.  I will be doing business with you for a very long time to come.  Thank You again."
Sheila OH, USA • February 2024
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"I have been a customer of Inhouse Pharmacy for *19 years*, I would wear your company logo on a t-shirt and bumper stickers if you sold them. If I didn't have Inhouse Pharmacy I don't even know what I'd do."
Catherine FL, USA • April 2023
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""Fantastic company to buy from with lovely helpful staff who are so good and help out with kindness""
Robin UK • February 2021
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"Thank you for everything over the years. You always provide wonderful customer service and that keeps me coming back to buy more every time!"
Breanna HI, USA • March 2023
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"I commend your exceptional service and for trusting me enough to send my order before receiving my payment. I feel compelled to march myself down to the mailbox with your check first thing in the morning. After all, service like yours deserves reciprocation."
John TX, USA • February 2020
 

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