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Anti-Androgens

Our Anti-Androgens class of Mens Health medications are used to block the action of testosterone in certain conditions including treating androgen-dependent prostate cancer and to treat hypersexuality.

Use the search feature to quickly find the product you are looking for, by entering either the active ingredient, e.g. cyproterone or the product name, e.g. Siterone.

What is an anti-androgen?

Anti-androgens are drugs that counteract the biological effects of the male hormone testosterone or its active metabolite DHT. They bind to the same androgen receptor as testosterone in specific cells and act as androgen receptor antagonists because they block the biological action of testosterone and DHT working through this receptor. Anti-androgens are either steroidal or non-steroidal and act in a competitive manner for the receptors.

Steroidal anti-androgens

Cyproterone is a steroidal anti-androgen that binds to the androgen receptor competing with testosterone and blocking testosterone binding to its receptor. However, cyproterone does have some biological effects, acting as a weak progestogen and glucocorticoid, which are other hormones involved in production of sex hormones like testosterone. This means that cyproterone does not prevent the production of testosterone completely but reduces the amount of testosterone produced. Cyproterone is used to treat hypersexuality (increased sex drive) and aggression in male sex offenders. It is also used to treat advanced prostate cancer.

Non-steroidal anti-androgens

Bicalutamide is a non-steroidal anti-androgen that binds to the androgen receptor but has no androgen or any other hormonal activity. It does not activate any normal testosterone actions, which means that it does not promote prostate cell growth or testosterone production. Bicalutamide is used to treat advanced prostate cancer, in combination with another medication that induces medical castration by preventing testosterone production by the testes. This blocks the stimulation by testosterone of cancer cell growth and helps slow or prevent progression of the tumour.
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"Package received! I want to thank you on behalf of my family for your wonderful service. My daughter cannot purchase domperidone in the States, and it is critical to her health. You have been a lifesaver. Thank you for making this drug available to her, and for the competent and courteous service your company provides. We are all grateful."
Rebecca McClear MI, USA • October 2025
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"As a satisfied customer of Inhouse Pharmacy for many years now, for both pet meds and personal use, I can confirm that the service provided is exemplary. From helpful people when I have queries, to efficient ordering and fast delivery (my most recent order arrived in the UK in a week), I'm more than happy to recommend them."
Jane UK • May 2026
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"I just received the inhalers and see that they don’t expire until next November, which is excellent! I really wanted to thank you again for all of your help and excellent customer service through this all. I’m sure it was a stressful time for your company as well. We will always continue ordering through your company."
Brooke Loffredo NJ,USA • October 2025
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Carole UK • January 2025
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"I've been an Inhouse customer for over 20 years. Exemplary customer service and very responsive if you have any questions or need any assistance with your orders!"
Dave MI, USA • May 2026
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"You guys are honestly top notch, especially in a world where access to healthcare is being constantly gate kept, you all are a force of good in that fight. Thank you! You guys really are the best! Please don't change."
Shane MI, USA • May 2026
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"Been using inhouse for about 6 years now and they've never let me down. On one occassion I was unable to get my parcel so I assumed I had lost money, but two weeks later they refunded me. Great company."
Katie Heys UK • June 2025
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"Hello, just a quick message to compliment you & your staff on maintaining such a high quality service. I have been a satisfied customer for too many years to count. While outside events ( an order seized by Customs) your company has kept every promise & made sure things were done to ensure delivery of products. I just want you to know that I can't think of any other company that is as excellent as Inhouse. The products offered are of top-notch quality. The customer service is incredibly effective & gracious in all communications. The updates on the order are wonderful, I know exactly how my order is moving thru the stages: order received/ order arranged for delivery/ order ready for mailing, tracking # given. It just hits all the check ✔️ marks. You folks blow other companies out of the water, just by doing things "right" & keeping communication lines open at every step.!! I appreciate you, & the other team members more than u will ever know. God Bless. "
Sandy Baker Michigian, USA • May 2026
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"I'll definitely be ordering from you again. Communication is super, better than any other company. Ordering was super easy. Thanks again. Gloria"
Gloria Bach NY, USA • April 2026
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"I have been a happy and satisfied customer of Inhouse Pharmacy for over 20 years. I have always been treated with great courtesy and my yearly order has always arrived between ten and twelve days after submitting the order. I would unqualifiedly recommend this company."
Wayne VA, USA • June 2026
 

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