Tiova Inhaler (Tiotropium) 200 Doses/Pack

Tiova Inhaler general information

What is Tiova Inhaler used for?

Tiova Inhaler 9mcg is used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD) and other obstructive airways disease, like chronic bronchitis, and emphysema.  Tiova Inhaler contains an aerosol that when inhaled relieves symptoms caused by bronchospasm (narrowing of the airways), such as shortness of breath, chronic cough with sputum production, tightness of the chest and wheezing.  Tiova Inhaler 9mcg also reduces the frequency of exacerbations and improves exercise tolerance and health-related quality of life, but does not cure COPD.

How does Tiova Inhaler work?

Tiova Inhaler 9mcg contains the bronchodilator tiotropium, which is a long-acting anticholinergic that acts on specific muscarinic receptors in the bronchioles of the lung to inhibit the interaction of acetylcholine (a neurotransmitter or chemical messenger of the nervous system) with muscarinic receptors, preventing spasm of the airway wall caused by acetylcholine.  Blocking the action of acetylcholine in the airways, causes the smooth muscle in the airway walls to relax and allows the airways to dilate (widen) which increases air flow into the lungs and relieves bronchospasm (narrowing of the airways).  Inhaled tiotropium goes directly into the lungs and very little is absorbed into the blood circulation.  Regular long-term use of Tiova helps reduce symptoms of COPD such as shortness of breath, chronic cough with sputum production, tightness of the chest and wheezing.

What does Tiova Inhaler contain?

Tiova Inhaler 9mcg contains the active ingredient tiotropium bromide monohydrate, a long-acting bronchodilator used to treat chronic obstructive pulmonary disease (COPD).  It also contains the hydrofluoroalkane non-CFC propellant HFA227, which delivers 9 mcg tiotroplum as an aerosol into the lungs each time you actuate (press down) your inhaler.  Each inhaler canister contains at least 120 actuations (doses). 

Treating chronic obstructive pulmonary disease (COPD) with Tiova Inhaler

Tiova Inhaler 9mcg contains the bronchodilator tiotropium, which relaxes the muscles of the airways, reducing bronchospasm (narrowing of the airways) and increasing air flow into the lungs.  Chronic obstructive pulmonary disease (COPD) is a progressive obstructive airways disease that usually gets worse with time, with symptoms similar to asthma caused by bronchospasm, including tightness of the chest, wheezing and shortness of breath, as well as chronic cough with sputum production because the lung tissues have become damaged.  Tiova Inhaler 9mcg relieves symptoms of bronchospasm, reduces the frequency of exacerbations and improves exercise tolerance and health-related quality of life, but Tiova Inhaler 9mcg does not cure COPD.  

What are the side effects of Tiova Inhaler?

The most commonly reported side effects when taking Tiova Inhaler include dry mouth and throat, cough, rapid heartbeat (tachycardia), blurred vision, high pressure in the eye (glaucoma), oral candida (thrush), dizziness, nausea, constipation, upset stomach, stuffy nose, nosebleed.

When should Tiova Inhaler not be used?

You should not use Tiova Inhaler if you:

• are allergic to tiotropium or any ingredients in Tiova Inhaler
• are pregnant or are breastfeeding
• have a history of hypersensitivity to atropine or its derivatives, (ipratropium or oxitropium)
• have severe kidney disease
• are having an acute episode of bronchospasm, as Tiova is not intended for rescue therapy
• have glaucoma, urinary problems, irregular heart beat, or prostate or kidney disease

How should Tiova Inhaler be taken?

You should use your Tiova Inhaler by taking 2 puffs per day each day and at the same time each day.  You should use your Tiova Inhaler 9mcg every day for as long as your doctor recommends, which may be long term. 

Follow the instructions provided with your Tiova Inhaler:

Remove the mouthpiece cover and shake the inhaler, breathe out as far as is comfortable and then place the mouthpiece in your mouth press down on the top of the inhaler to release a dose of tiotropium while still breathing in through your mouth and hold your breath for a few seconds, then breathe normally.  Repeat for the second dose.  Replace the mouthpiece cover.   

Note:  You can use your inhaler with a spacer Zerostat/Zerostat VT device to help you inhale correctly.

How long should you take Tiova Inhaler?

Tiova Inhaler 9mcg is intended for long-term use and you should take your Tiova Inhaler every day for as long as your doctor recommends.

Missed dose of Tiova Inhaler

If you miss a dose of Tiova Inhaler 9mcg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Tiova Inhaler be stored?

You should store your Tiova Inhaler below 25°C in a cool dry place keep away from direct sunlight.