Suminat (Sumatriptan) 100mg Tablets

Suminat-100 general information

What is Suminat-100 used for?

Suminat-100 100mg tablets (generic Imigran) are used to relieve acute migraine attacks with or without aura, which is the perception of visual disturbances and/or smells and are usually the first sign that a migraine headache is on its way. Suminat-100 rapid release tablets are specific for treatment of migraine attack to relieve headache and other symptoms, including nausea and sensitivity to light, but they are not used to prevent migraine headaches. You can use Suminat-100 rapid release tablets at any stage of a migraine attack but it is more effective if taken as soon as possible after the first signs of headache and/or aura. Suminat-100 is not used for treatment of other types of headache.

How does Suminat-100 work?

Suminat-100 100mg tablets contain sumatriptan, which is a member of the group of drugs called tryptans and is a serotonin agonist that mimics the action of serotonin (also known as 5-hydroxytryptamine, or 5-HT). Serotonin is a brain chemical that is involved in control of mood, pain sensation, sexual behaviour, sleep, as well as dilation (widening) and constriction (narrowing) of blood vessels. Migraine is thought to be caused by dilatation or widening of blood vessels in the head due to one of many migraine triggers, which in turn stimulates nearby sensory nerves so that you feel pain. Sumatriptan in Suminat-100 rapid release tablets stimulates the serotonin receptors in these expanded blood vessels making them narrow again (vasoconstriction) and inhibits trigeminal nerve activity, relieving pain. Both actions are thought to contribute to the anti-migraine action of sumatriptan and relieve headache and other symptoms of a migraine attack. Suminat-100 rapid release tablets are formulated using rapid release fast disintegration technology. They work is the same way as other sumatriptan-containing migraine tablets but are effective sooner, usually within two hours, because they dissolve faster in the stomach after swallowing. Therefore, the active ingredient sumatriptan is released more rapidly, which speeds up absorption into the blood and reduces the time taken to reach its target receptors in the brain.

What does Suminat-100 contain?

Suminat-100 100mg tablets contain the active ingredient sumatriptan, which is a serotonin agonist and causes dilated blood vessels in the head to constrict relieving headache and other symptoms of a migraine attack.

Treating migraine headache with Suminat-100

Suminat-100 100mg tablets contain sumatriptan, which is a serotonin agonist that mimics the action of serotonin. They are used to relieve acute migraine attacks with or without aura, which is the perception of visual disturbances and/or smells called and are usually the first sign that a migraine headache is on its way. Migraine is thought to be caused by dilatation or widening of blood vessels in the head due to one of many migraine triggers, which in turn stimulates nearby sensory nerves so that you feel pain. Sumatriptan in Suminat-100 rapid release tablets stimulates the serotonin receptors in these expanded blood vessels making them narrow again (vasoconstriction) and inhibits trigeminal nerve activity, relieving pain. Both actions are thought to contribute to the anti-migraine action of sumatriptan in Suminat-100 to relieve headache and other symptoms of a migraine attack. Suminat-100 rapid release tablets are formulated using rapid release fast disintegration technology. They work is the same way as other sumatriptan-containing migraine tablets but are effective sooner, usually within two hours, because they dissolve faster in the stomach after swallowing. Therefore, the active ingredient sumatriptan is released more rapidly, which speeds up absorption into the blood and reduces the time taken to reach its target receptors in the brain. Suminat-100 rapid release tablets relieve the headache and other symptoms of migraine, including nausea and sensitivity to light.

What are the side effects of Suminat-100?

The most commonly reported side effects when taking Suminat-100 100mg tablets include dizziness, drowsiness, sensory disturbance including, tingling, pricking, or numbness of the skin (paraesthesia), loss of sensitivity to pain or touch (hypoaesthesia), shortness of breath, sensations of heaviness, pain, sensations of heat or cold, pressure or tightness, weakness, fatigue.

When should Suminat-100 not be used?

You should not use Suminat-100 if you:

• are allergic to sumatriptan or any ingredients in Suminat-100 100mg tablets
• have had myocardial infarction or have ischaemic heart disease, coronary vasospasm (Prinzmetal's angina), peripheral vascular disease, or a history of cerebovascular accident (CVA) or transient ischaemic attack (TIA)
• have liver disease or hypertension
• are using medicines that interact with Suminat-100, including: ergotamine or derivatives of ergotamine (including methysergide), monoamine oxidase inhibitors (MAOIs)

What medications interact with Suminat-100?

The following medications interact with Suminat-100 and should either not be taken while you are taking Suminat-100 or only after discussion and instruction from your doctor.

• Ergot derivatives including methysergide (also for migraine headaches) should not be taken 24 hours before to 6 hours after dose of Suminat-100
• MAOI antidepressants should not be taken within 14 days of Suminat-100
• Other serotonin agonist antidepressants like SSRIs; SNRIs.

How should Suminat-100 be taken?

You can use Suminat-100 100mg tablets at any stage of a migraine attack but it is more effective if taken as soon as possible after the first signs of headache and/or aura. You should take one Suminat-100 rapid release tablet with a glass of water, with or without food. You should not take another dose of Suminat-100 for the same migraine, but you can take another dose if you have another migraine attack in the next 24 hours, provided you do not take more than 300mg in a 24 hour period.

How should Suminat-100 be stored?

You should keep your Suminat-100 rapid release tablets in their pack until use. Store you Suminat-100 100mg tablets in a cool dry place below 30°C.