Clindac A (Clindamycin phosphate 1%)

Clindac A Topical Solution general information

What is Clindac A Topical Solution used for?

Clindac A Topical Solution 1% is used to treat mild inflammatory acne vulgaris of the face, chest or back, including pimples (papules), whiteheads (pustules) and blackheads (comedones).  Clindac A is a topical antibiotic for acne that has become infected and is unresponsive to non-antibiotic treatment.  Clindac A Topical Solution gets into the lesions that form on the skin and kills the bacteria, clearing up the infection and preventing spread of the infection.  

How does Clindac A Topical Solution work?

Clindac A Topical Solution 1% is contains the active ingredient clindamycin phosphate, which is an antibiotic belonging to the lincomycin group of antibiotics.  Clindamycin in Clindac A Topical Solution 1% blocks protein synthesis in the bacteria responsible for causing infection of acne affected skin, and this kills the bacteria.  Propionibacterium acnes are bacteria that normally exist on the skin without causing any problems, living on fatty acids in the sebum (oil) secreted by the sebaceous glands (oil producing glands in hair follicles of the skin).  Over production of sebum causes the pores of the skin to become blocked and this is how the pimples, whiteheads and blackheads (comedones) of acne form.  Clogged pores attract bacteria which then overgrow and cause infection.  Clindamycin in Clindac A solution gets into the blackheads and blocks the growth of the bacteria, while at the same time reducing the amount of fatty acids that the bacteria live on.  This action of Clindac A solution reduces bacterial growth that contributes to formation of acne skin lesions and prevents the spread of infection.    

What does Clindac A Topical Solution contain?

Clindac A Topical Solution 1% contains the active ingredient clindamycin phosphate, an antbiotic that kills the bacteria responsible for causing infection of acne affected skin, at a concentration equivalent to 10 mg/mL.

Treating acne with Clindac A Topical Solution

Clindac A Topical Solution 1% contains clindamycin, a topical antibiotic that is used to treat acne that has become infected and is unresponsive to non-antibiotic treatment.  Acne forms when over stimulation of the sebaceous glands (oil producing glands in hair follicles), which often happens in response a surge of androgen hormones at puberty, causes pores to become clogged with dead skin.  This leads to the formation of new pimples, whitehead and blackheads (comedones), which can become infected and inflamed.  Clindamycin in Clindac A Topical Solution 1% blocks protein synthesis in the bacteria responsible for causing infection of acne affected skin.  This prevents the overgrowth of bacteria that normally exist on the skin without causing any problems; living on fatty acids in the sebum (oil) secreted by the sebaceous glands and prevents the spread of infection.   

What are the side effects of Clindac A Topical Solution?

The most commonly reported side effects when taking Clindac A Topical Solution include burning, itching, dryness or irritated skin at the site of application.  Clindamycin phosphate in Clindac A Topical Solution can be absorbed through the skin and may cause systemic side effects including gastrointestinal disturbances like diarrhoea, bloody diarrhoea and colitis.

When should Clindac A Topical Solution not be used?

You should not use Clindac A Topical Solution if you:

• are allergic to clindamycin or any ingredients in Clindac A Topical Solution
• are pregnant or are breastfeeding
• have a history of enteritis, ulcerative colitis or antibiotic-associated colitis
• are using other anti-acne or comedogenic cosmetic products

How should Clindac A Topical Solution be applied?

You should apply your Clindac A Topical Solution to the affected area of the skin twice daily morning and evening.  Clean the skin with a mild soap or soap-free cleanser, rinse with water and dry, then apply a small amount, using the applicator provided, and then with clean fingers rub gently into the affected area of skin.  Wash your hands well after use and avoid contact with your eyes or inside your nose and mouth.  Avoid concurrent use of topical preparations containing alcohol, such as astringents or medicated cosmetics as they potentiate the drying action on the skin.  You should continue to use your Clindac A Topical Solution until your infection has cleared up or for as long as recommended by your doctor. 

How long should you take Clindac A Topical Solution?

You should continue to use your Clindac A Topical Solution until your infection has cleared up or for as long as recommended by your doctor. 

Missed dose of Clindac A Topical Solution

If you miss a dose of Clindac A Topical Solution apply it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not apply a double dose.

How should Clindac A Topical Solution be stored?

You should store your Clindac A Topical Solution below 25°C in a cool dry place.