Fluconazole 150mg

Fluconazole general information

What is Fluconazole used for?

Fluconazole capsules 150mg are used to treat vaginal candidiasis (vaginal thrush) a yeast infection of the vagina with characteristic symptoms including vaginal itching and soreness, and white, odourless, discharge from the vagina.  Fluconazole capsules 150mg are intended as a one-off oral treatment and should provide relief of symptoms after the first day, although it may take several days to be fully effective. 

How does Fluconazole work?

Fluconazole capsules 150mg contain fluconazole, which is a broad-spectrum antifungal drug belonging to the triazole group of antifungals.  Fluconazole in Fluconazole capsules 150mg is a potent and specific inhibitor of fungal enzymes necessary for the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells.  Fluconazole in Fluconazole capsules 150mg weakens the fungal cell membrane, causing the cell contents to leak out which kills the fungus, preventing the infection from spreading and relieving symptoms caused by the infection, including, itching and inflammation.    

What does Fluconazole contain?

Fluconazole capsules 150mg contain the active ingredient fluconazole, a broad-spectrum antifungal used to treat vaginal candidiasis.  They also contain lactose, maize starch, sodium lauryl sulphate, colloidal hydrated silica, magnesium stearate, gelatin, titanium dioxide (E171), shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, potassium hydroxide and black iron oxide (E172).

Treating vaginal thrush with Fluconazole

Fluconazole capsules 150mg contain fluconazole, a synthetic broad-spectrum antifungal agent that is used to treat vaginal candidiasis (vaginal thrush), caused by the yeast Candida albicans.  The most common sites of thrush infection are the mucous membranes particularly of the vagina.  Fluconazole in Fluconazole capsules 150mg specifically inhibit the synthesis of ergosterol, an important component of the fungal cell membrane, which kills the fungus and stops it spreading.  Fluconazole capsules 150mg relieve the symptoms of vaginal thrush, including vaginal itching and soreness, and white, odourless, discharge from the vagina.  Fluconazole capsules 150mg are intended as a one-off oral treatment and should provide relief of symptoms after the first day, although it may take several days to be fully effective.

What are the side effects of Fluconazole?

The most commonly reported side effects when taking Fluconazole capsules 150mg include headache, nausea and vomiting, diarrhoea, abdominal pain, dyspepsia (indigestion), skin rash.

When should Fluconazole not be used?

You should not use Fluconazole capsules 150mg if you:

• are allergic to fluconazole or any ingredients in Fluconazole capsules
• are pregnant or are breastfeeding, without discussion with your doctor
• have kidney or liver disease or a heart condition
• are taking medicines that interact with Fluconazolethe antiviral rifampicin, rifabutin or zidovudine; terfenadine or astemizole for allergy, cisapride for reflux, the anticonvulsant phenytoin, the diuretic hydrochlorothiazide, oral antidiabetics like glipizide, tolbutamide or glibenclamide, theophylline for asthma, the immunosuppressants tacrolimus and cyclosporine, some benzodiazepines such as midazolam

What medications interact with Fluconazole?

Several medications interact with Fluconazole capsules 150mg and should either not be taken while you are taking Fluconazole or only after discussion and instruction from your doctor:

• Drugs that cause increased side effects with Fluconazole: cisapride for reflux can cause heart problems
• Drugs that affect Fluconazole: the antiviral rifampicin, rifabutin or zidovudine; the diuretic hydrochlorothiazide
• Drugs that are affected by Fluconazole: the anticonvulsant phenytoin, oral antidiabetics like glipizide, tolbutamide or glibenclamide; theophylline for asthma, immunosuppressants tacrolimus and cyclosporine, some benzodiazepines such as midazolam

How should Fluconazole be taken?

You should take your Fluconazole capsule 150mg swallowed whole with a glass of water, with or without food and at any time of day.  You should take Fluconazole capsule 150mg only as single dose as it is intended as a one-off oral treatment.  Your symptoms should start to disappear after the first day, although it may take several days to be fully effective.  

How long should you take Fluconazole?

You should take Fluconazole capsule 150mg only as single dose as it is intended as a one-off oral treatment. 

How should Fluconazole be stored?

You should store your Fluconazole capsules 150mg below 25°C in a cool dry place.