Amacin Ear & Eye Ointment 4g

Amacin general information

What is Amacin used for?

Amacin Eye and Ear ointment is combination medication used to treat most common eye and ear conditions caused by bacterial infection in dogs and cats.  These conditions include, conjunctivitis, which is inflammation of the conjunctiva, the outermost layer of the eye and the inside of the eyelid; superficial keratitis or inflammation of the cornea (the clear area at the front of the eye over the lens and pupil); and otitis externa, which is infection of the outer ear.  Amacin Eye and Ear ointment is also used to treat primary or secondary wounds, or allergic reaction of the skin that have become infected.  Amacin Eye and Ear ointment helps relieve symptoms of eye and ear infection including sore eyes, redness, inflammation, discharge and crusting around the eyelid.  

How does Amacin work?

Amacin Eye and Ear ointment contains a corticosteroid and three antibiotics used in combination to treat bacterial infection and inflammation of the eye and ear in cats and dogs.  Prednisolone in Amacin Eye and Ear ointment is a synthetic derivative of the natural corticosteroid hormone cortisol, with potent anti-inflammatory properties, and works by reducing the vascular (blood vessels) and cellular inflammatory response that triggers inflammation, primarily by blocking the production of inflammatory chemicals, like prostaglandins and leukotrienes from inflammatory cells; also by preventing the migration of inflammatory cells into inflamed tissues.  This action of Prednisolone in Amacin Eye and Ear ointment reduces the swelling, redness and pain associated with inflammation.  Neomycin in Amacin Eye and Ear ointment is a broad-spectrum aminoglycoside antibiotic that is used in topical medications and is effective against wide range of bacteria found in infected skin, including Staphylococcus, Pseudomonas and Proteus species.  Neomycin in Amacin Eye and Ear ointment works by blocking bacterial protein synthesis and inhibiting the production of proteins needed for bacterial cell growth.  The antibiotic Polymyxin in Amacin Eye and Ear ointment is only effective Gram negative bacteria like Pseudomonas aeruginosa and Escherichia coli, and is often used in combination with another antibiotic for topical bacterial infection.  Polymyxin in Amacin Eye and Ear Ointment works by disrupting the bacterial cell membrane, which makes it more permeable and the bacteria more susceptible to the effects of other antibiotics.  Sulfacetamide is a sulphonamide antibiotic used in topical applications, is rapidly absorbed into the surfaces of the eye and ear and works by blocking bacterial synthesis of folic acid which is essential for bacterial cell growth.  The combined antibacterial and anti-inflammatory action of Amacin Eye and Ear ointment relieves symptoms of inflammation and prevents spread of infection.

What does Amacin contain?

Amacin Eye and Ear ointment contains the active ingredients, prednisolone a corticosteroid, and the antibiotics neomycin, polymyxin and sulfacetamide, which are used in combination to treat bacterial infection and inflammation of the eye and ear in cats and dogs. 

Treating ear and eye infections with Amacin

Amacin Eye and Ear ointment contains the corticosteroid prednisolone and the antibiotics neomycin, polymyxin and sulfacetamide, which are used in combination to treat most common ear and eye conditions caused by bacterial infection in dogs and cats.  These conditions include, conjunctivitis, which is inflammation of the conjunctiva, the outermost layer of the eye and the inside of the eyelid; superficial keratitis or inflammation of the cornea (the clear area at the front of the eye over the lens and pupil); and otitis externa, which is infection of the outer ear.  Amacin Eye and Ear ointment is also used to treat primary or secondary wounds, or allergic reaction of the skin that have become infected.  Amacin Eye and Ear ointment helps relieve symptoms of eye and ear infection including sore eyes, redness, inflammation, discharge and crusting around the eyelid.  Prednisolone in Amacin Eye and Ear ointment is a corticosteroid with potent anti-inflammatory properties, and works by reducing the vascular (blood vessels) and cellular inflammatory response that triggers inflammation, primarily by blocking the production of inflammatory chemicals, like prostaglandins and leukotrienes from inflammatory cells; also by preventing the migration of inflammatory cells into inflamed tissues.  Neomycin in Amacin Eye and Ear ointment is a broad-spectrum aminoglycoside antibiotic that is used in topical medications and is effective against wide range of bacteria found in infected skin and works by blocking bacterial protein synthesis and inhibiting the production of proteins needed for bacterial cell growth.  The antibiotic Polymyxin in Amacin Eye and Ear ointment is often used in combination with another antibiotic for topical bacterial infectionand works by disrupting the bacterial cell membrane, which makes it more permeable and susceptible to the effects of other antibiotics.  Sulfacetamide is a sulphonamide antibiotic used in topical applications, is rapidly absorbed into the surfaces of the eye and ear and works by blocking bacterial synthesis of folic acid which is essential for bacterial cell growth.  The combined antibacterial and anti-inflammatory action of Amacin Eye and Ear ointment relieves symptoms of inflammation like swelling, redness and pain and prevents spread of infection.

What are the side effects of Amacin?

The most commonly reported side effects when taking Amacin Eye and Ear ointment include irritation, burning, itching, stinging and dermatitis due to hypersensitivity reaction; blurred vision, raised intraocular pressure, cataract, delayed healing in the eye.

When should Amacin not be used?

You should not use Amacin Eye and Ear ointment for your cat or dog if your pet:

• is allergic to prednisolone, neomycin, polymyxin or sulfacetamide or any ingredients in Amacin
• is pregnant or lactating
• has a viral or fungal eye infection
• has herpetic keratitis (herpes infection of the eye)
• is taking a systemic aminoglycoside antibiotic
• is taking medicines that interact with Amacin including topical steroids or NSAID

How should Amacin be used?

You should apply Amacin Eye and Ear ointment to your pet’s ear by instilling a small amount of ointment into the ear, and into the eye by pulling down the lower eyelid to form a pouch and squeezing a small amount of ointment into the pouch.  How often and for how long you give Amacin Eye and Ear ointment to your pet depends on what they are being treated for and your veterinarian’s recommendation, which may be up to 3-4 times daily.  Wash your hands before and after use and do not let the tip of the tube touch the eye.  You should continue to apply Amacin Eye and Ear ointment for as long as recommended by your veterinarian.

How long should you take Amacin?

You should continue to apply Amacin Eye and Ear ointment for as long as recommended by your veterinarian.

Missed dose of Amacin

If you miss a dose of Amacin Eye and Ear ointment apply it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Amacin be stored?

You should store your Amacin Eye and Ear ointment below 25°C in a cool dry place but do not refrigerate.