Posatex Ear Drops (Orbifloxacin/Mometasone/Posaconazole ) Ear Suspension 17.5ml

Posatex Ear Drops general information

What is Posatex Ear Drops used for?

Posatex Ear Drops are a combination medication used as a topical treatment for chronic and acute otitis externa in dogs; also, to prevent acute exacerbations of recurrent otitis externa.  Otitis externa is an infection of the outer ear that is caused by fungi and/or bacteria.  Posatex Ear Drops are also effective for treating inflammation that is caused by the infection and helps relieve symptoms including itching, discomfort, redness and swelling. 

How does Posatex Ear Drops work?

Posatex Ear Drops contain a combination of three topical medications used together to treat otitis externa in dogs.  Orbifloxacin in Posatex Ear Drops is a fluoroquinolone antibiotic and is effective against a wide range of susceptible bacteria that can cause ear infection in dogs, including Pseudomonas aeruginosa, enterococcus faecalis and coagulase positive staphylococci.  It works by inhibiting the DNA topoisomerase II (DNA-gyrase) and DNA topoisomerase IV enzymes that are needed for the synthesis of bacterial DNA, which prevents bacterial replication and kills the bacteria. Posaconazole in Posatex Ear Drops is a broad spectrum antifungal used to treat fungal infections of the skin.  It is effective against the yeast Malassezia pachydermatis (formerly Pityrosporum canis) that causes ear infections in dogs.  Posaconazole in Posatex Ear Drops works by inhibiting the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells.  This weakens the fungal cell membrane causing the cell contents to leak out killing the fungus.  Mometasone in Posatex Ear Drops is synthetic corticosteroid that works as an effective anti-inflammatory by blocking the production of inflammatory chemicals like prostaglandins and leukotrienes.  The three components of Posatex Ear Drops work together to fight the infection that causes otitis; they also help relieve symptoms of inflammation caused by the infection.    

What does Posatex Ear Drops contain?

Posatex Ear Drops contains the active ingredients orbifloxacin 0.1%, mometasone 1%, posaconazole 0.1% in a mineral oil based system.

Treating otitis in dogs with Posatex Ear Drops

Posatex Ear Drops contains combination of active ingredients that work together to treat chronic and acute otitis externa in dogs, which is infection and inflammation of the outer ear, caused by a yeast fungal infection and/or a bacterial infection.  Posatex Ear Drops are also effective for treating inflammation that is caused by the infection and helps relieve symptoms including itching, discomfort, redness and swelling.  Orbifloxacin in Posatex Ear Drops is an antibiotic effective against a wide range of susceptible bacteria that can cause ear infection in dogs, and works by inhibiting the specific enzymes needed for synthesis of bacterial DNA, which prevents bacterial replication and kills the bacteria. Posaconazole in Posatex Ear Drops is a broad spectrum antifungal that is effective against yeasts and fungi that cause ear infections in dogs.  It works by inhibiting the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells, which weakens the fungal cell membrane causing the cell contents to leak out killing the fungus.  Mometasone in Posatex Ear Drops is a topical steroid that works as an effective anti-inflammatory by blocking the production of inflammatory chemicals like prostaglandins and leukotrienes.  The three components of Posatex Ear Drops work together to fight the infection that causes otitis; they also help relieve symptoms of inflammation caused by the infection.

What are the side effects of Posatex Ear Drops?

The most commonly reported side effects when taking Posatex Ear Drops include deafness or partial hearing loss and erythematous lesions (red scaly patches on the skin); also symptoms of long-term corticosteroid use like immunosuppression. 

When should Posatex Ear Drops not be used?

You should not use Posatex Ear Drops if your dog:

• is allergic to orbifloxacin, mometasone, posaconazole or any ingredients in Posatex Ear Drops
• Has a perforated eardrum
• Is less than 4 months old as joint damage can occur in young animals that are still growing
• Is pregnant or lactating

How should Posatex Ear Drops be given?

You should clean and dry your dog’s ear before applying Posatex Ear Drops, remove any debris or crusting with a non-irritable solution and clip away any hair that would get in the way of treatment.  Shake well before use, then add the appropriate number of drops of Posatex Ear Drops into your dog’s ear, depending on their size and massage the ear to ensure it has penetrated into the ear and distributed evenly.  Avoid contact with the eyes. You should give Posatex Ear Drops to your dog once daily for 7 days but no longer as continued used could prevent wound healing.  

Dosage:

• Less than 2 kg (4.4lb) 2 drops
• 2 (4.4lb) - 15 kg (33lb) 4 drops
• 15 kg (33lb) or more 8 drops

How long give you take Posatex Ear Drops?

You should give Posatex Ear Drops to your dog once daily for 7 days but no longer as continued used could prevent wound healing.  

Missed dose of Posatex Ear Drops

If you miss a dose of Posatex Ear Drops give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Posatex Ear Drops be stored?

You should store your Posatex Ear Drops below 25°C in a cool dry place.