Doxine (Doxycycline hyclate 100mg) Tablets

Doxine general information

What is Doxine used for?

Doxine tablets 100 mg are a broad-spectrum antibiotic used to treat a wide range of bacterial infections in various parts of the body. Conditions that Doxine tablets 100 mg are used for include chest infections like pneumonia and bronchitis; urinary tract infections; sexually transmitted diseases; Infections due to Chlamydia including uncomplicated urethral, endocervical or rectal infections; some bacterial eye infections like trachoma, caused by Chlamydia. Doxine tablets 100 mg are also used to treat severe acne; and with other medicines to treat intestinal amoebiasis, a parasitic gut infection.

​Doxine use in Lyme Disease

Doxine tablets 100 are also used to treat Lyme disease, which is caused by infection with the bacteria Borrelia, transmitted by a bite from the black-legged tick or deer tick and is the most common tick-borne infection in both North America and Europe.  Symptoms of Lyme disease include erythema migrans, a circular spreading rash, flu-like symptoms, joint pain and neurological problems.  Doxine tablets 100mg are also useful for treating infections with Rickettsiae, which is a bacteria transmitted by ticks and lice and causes infections like rocky mountain spotted fever and typhus fever.

How does Doxine work?

Doxine tablets 100 contain Doxycycline, which is a broad-spectrum antibiotic belonging to the tetracycline group of antibiotics, with antibacterial activity against a wide range of bacteria, including Rickettsiae, Chlamydia, Streptococcus, Haemophilus, Klebsiella, Mycoplasma. Doxycycline in Doxine tablets 100mg inhibits protein synthesis in susceptible bacteria by blocking the transcription stage, which is reading the protein message from the bacterial RNA. This action prevents the bacteria from producing essential proteins needed for growth, repair and replication and prevents the spread of infection.

What does Doxine contain?

Doxine tablets 100 contain the active ingredient doxycycline hyclate, a broad-spectrum antibiotic, used to treat a wide range of bacterial infections. They also contain microcrystalline cellulose, pregelatinised maize starch, colloidal silicon dioxide, and magnesium stearate. The tablet coating contains hypromellose, hydroxypropyl cellulose, titanium dioxide (E171), quinoline yellow lake (E104), iron oxide yellow (E172) and carnauba wax.

Treating bacterial infection with Doxine

Doxine tablets 100mg contain Doxycycline, which is a broad-spectrum antibiotic used to treat bacterial infections caused by a wide range of susceptible bacteria in various parts of the body, including chest infections like pneumonia and bronchitis; urinary tract infections; sexually transmitted diseases Infections due to Chlamydia and some bacterial eye infections like trachoma, caused by Chlamydia. Doxine tablets 100mg are also used to treat Lyme disease, which is caused by infection with the bacteria Borrelia, transmitted by a bite from the black-legged tick or deer tick and is the most common tick-borne infection in both North America and Europe.  Symptoms of Lyme disease include erythema migrans, a circular spreading rash, flu-like symptoms, joint pain and neurological problems.  Doxine tablets 100 mg are also useful for treating infections with Rickettsiae, which is a bacteria transmitted by ticks and lice and causes infections like rocky mountain spotted fever and typhus fever.  Doxine tablets 100 mg are also used to treat severe acne, where bacterial infection has developed. Doxine tablets 100 block bacterial protein synthesis which prevents the bacteria from producing essential proteins needed for growth, repair and replication which stops the spread of infection. This action helps relieve symptoms of the bacterial infection, which include inflammation and pain.

What are the side effects of Doxine?

The most commonly reported side effects when taking Doxine tablets 100mg include: anorexia, diarrhoea, nausea, sore tongue (glossitis), difficulty swallowing (dysphagia), heartburn or indigestion due to irritation of the oesophagus, inflammation of the colon (enterocolitis), swelling and itching in the anal and genital areas, staining of the teeth, loss of tooth enamel.

When should Doxine not be used?

You should not use Doxine if you:

• are allergic to doxycycline or other tetracycline antibiotics or any other ingredients in Doxine tablets 100mg
• are pregnant, plan to become pregnant or are breastfeeding
• are under 12 years of age
• are taking other medication that interacts with Doxine tablets, including penicillin antibiotics, barbiturates, phenytoin for epilepsy, the anticoagulant warfarin
• are taking supplements or vitamins that contain iron preparations, which may reduce the absorption of doxycycline

How should Doxine be taken?

You should take your Doxine tablets 100mg once daily with a glass of water with food, preferably just before a meal, to reduce stomach effects. The dose you take should be as recommended by your doctor, usually 2 tablets on the first day and then 1 tablet for the rest of your prescribed course, which may be a few days or weeks, depending on what you are being treated for. You should continue to take your tablets even if you feel better, until you have completed the prescribed course of treatment.

How long should you take Doxine?

You should continue to take your Doxine tablets 100mg for as long as recommended by your doctor, which will depend on what you are being treated for.

Missed dose of Doxine

If you miss a dose of Doxine tablets 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Doxine be stored?

You should store your Doxine tablets 100mg below 25°C in a cool dry place out of direct sunlight.