Bioclan (Clindamycin 300mg) Easy Chews

Bioclan general information

What is Bioclan used for?

Bioclan chewable tablets 150mg are an antibiotic medication used for the treatment of serious bacterial infections in dogs caused by susceptible bacteria.  These include superficial pyoderma (superficial skin infection), wounds and abscesses, infected mouth cavity and dental infections; also to prevent infection due to dental surgery.  Bioclan chewable tablets 150mg are also used to treat osteomyelitis (infection of the bone or bone marrow), which may be caused by an infection from another part of the body reaching the bone through the blood, or the bone may become infected from an accident involving the bone.  Bioclan chewable tablets 150mg are meaty flavoured to make them more palatable.  Bioclan chewable tablets 150mg are specially formulated for treatment of bacterial infections in dogs.

How does Bioclan work?

Bioclan chewable tablets 150mg contain clindamycin, a lincosamide antibiotic with bacteriostatic action that is used to treat a wide range of serious bacterial infections in dogs.  Clindamycin in Bioclan chewable tablets 150mg is effective against a range of sensitive bacteria including Staphylococcus aureus and intermedius, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.  Clindamycin in Bioclan chewable tablets 150mg works by binding to the bacterial ribosome, a structure involved in protein synthesis and this inhibits the early stages of bacterial protein synthesis, so that the bacteria cannot make important proteins required for survival of the bacteria, which inhibits bacterial growth and prevents the spread of infection.  Clindamycin in Bioclan chewable tablets 150mg is lipid soluble and, therefore, penetrates many body fluids and tissues, such as soft tissue, bone and joints; it also penetrates biofilms found in dental and bone infections.  It is rapidly absorbed and concentrates in the white blood cells at the site of infection and begins to take effect within 30 minutes.   

What does Bioclan contain?

Bioclan chewable tablets 150mg contain the active ingredient clindamycin hydrochloride, an antibiotic that is used to treat a wide range of serious bacterial infections in cats and dogs.  They also contain iron oxide red.

Treating bacterial infection with Bioclan

Bioclan chewable tablets 150mg contain clindamycin, an antibiotic that is used to treat a wide range of serious bacterial infections in dogs.  These include superficial pyoderma (superficial skin infection), wounds and abscesses, infected mouth cavity and dental infections; also to prevent infection due to dental surgery.  Bioclan chewable tablets 150mg are also used to treat osteomyelitis (infection of the bone).  Clindamycin in Bioclan chewable tablets 150mg works by binding to the bacterial ribosome, a structure involved in protein synthesis and this inhibits the early stages of bacterial protein synthesis, so that the bacteria cannot make important proteins required for survival of the bacteria, which inhibits bacterial growth and prevents the spread of infection. 

What are the side effects of Bioclan?

The most commonly reported side effects when taking Bioclan chewable tablets 150mg include vomiting and diarrhoea.  Clindamycin may cause overgrowth of non-sensitive organisms like yeast and the toxin-producing bacterium clostridium in the intestines, which can cause intestinal problems.

When should Bioclan not be given?

You should not give Bioclan chewable tablets 150mg to your pet if your dog:

• is allergic to clindamycin or any ingredients in Bioclan
• is pregnant or lactating
• has kidney or liver disease
• is taking medicines that interact with Bioclan including the antibiotic erythromycin; neuromuscular blockers

How should Bioclan be given?

You should give your dog Bioclan chewable tablets 150mg once or twice daily depending on what they are being treated for and the dose given should be according to body weight.  You should continue to give Bioclan chewable tablets 150mg for as long as recommended by your veterinary professional which ranges from 7-28 days, depending on what your dog is being treated for.

Bioclan chewable tablets are available as 150mg and 300mg. 

• For dogs less than 4.5kg (9.9lb) you should use oral solution 25mg/ml.
• 13.5kg (30lb) bodyweight     one 150mg tablet
• 27kg (60lb) bodyweight       one 300mg tablet

For superficial skin infections: 5.5 mg/kg (12lb/kg) every 12 hours or 11 mg/kg (24lb/kg) every 24 hours for 21 days:

For Dental infections, wounds and abscesses: 5.5 mg/kg (12lb/kg) every 12 hours or 11 mg/kg (24lb/kg) every 24 hours for 7-10 days

For osteomyelitis: 11 mg/kg (24lb/kg) every 24 hours or every 12 hours for 28 days

How long should you take Bioclan?

You should continue to give Bioclan chewable tablets 150mg for as long as recommended by your veterinary professional which ranges from 7-28 days, depending on what your pet is being treated for.

Missed dose of Bioclan

If you miss a dose of Bioclan chewable tablets 150mg give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Bioclan be stored?

You should store your Bioclan chewable tablets 150mg below 25°C in a cool dry place.