Kiwof Plus XL for Large and Extra Large Dogs

Kiwof Plus XL XL general information

What is Kiwof Plus XL used for?

Kiwof Plus XL Easy Chew tablets 175/504/524 are used as a multi spectrum de-wormer for dogs, and are suitable for medium and large dogs, but nor for puppies or cats.  Kiwof Plus XL Easy Chews are effective in the control of all common gastrointestinal worms.  These include the roundworms (ascarids) Toxicara canis and Toxascaris leonine; the hookworms Ancylostoma caninum and Uncinaria stenocephala; and the whipworm Trichuris vulpis.  They are also effective against intestinal tapeworms (cestodes), including Dipylidium caninum, Taenia taeniaformis, Echinococcus granulosus and Echincoccus multilocularis, and for removal and control of the hyatid cyst, which is the larval form of the tapeworm.  Kiwof Plus XL Easy Chews can also be used in combination with other treatments such as medications for the prevention of heartworm, fleas and ticks; also, vaccinations, but should not be used in combination with other deworming medications.  Kiwof Plus XL Easy Chews can be given directly to the dog or disguised in food and are easy to use.

How does Kiwof Plus XL work?

Kiwof Plus XL Easy Chew tablets 175/504/524 contain a combination of three anthelmintic drugs, which is a drug that kills and dispels parasitic worms (helminths).  Praziquantel in Kiwof Plus XL Easy Chews is an anthelmintic that is effective against intestinal tapeworms (cestodes) and works by interfering with the tapeworm’s ability to protect itself against its host, causing the tapeworm to lose resistance to digestion by the host’s digestive enzymes.  The tapeworm becomes disintegrated and is then removed by the host’s immune system, which destroys the tapeworm before it can be passed out in stools.  Pyrantel in Kiwof Plus XL Easy Chews is a depolarising neuromuscular blocking agent that is effective against roundworms and hookworms that attach to the wall of the host’s intestine by small teeth or suckers.  It works by blocking nerve transmission causing sudden muscular contraction followed by paralysis.  This causes the worm to lose its grip on the intestine wall and fall off; it then becomes paralysed and dies and is passed out in the stools.  Febantel in Kiwof Plus XL Easy Chews is inactive but is converted to fenbendazole a benzimidazole anthelmintic, which has a broad spectrum action.  Fenbendazole works by binding to tubulin in the worm cells, a structural protein of microtubules, and this blocks glucose uptake, which depletes energy stores and eventually paralyses the parasite, which then dies.  Although these drugs are effective against parasitic worms in the intestine, they are not well absorbed into the blood of the host and therefore, have minimal side effects. 

What does Kiwof Plus XL contain?

Kiwof Plus XL Easy Chews contain a combination of three the active ingredients, the anthelmintic drugs praziquantel (175mg) pyrantel pamoate (504mg), febantel (525mg) that are used in combination as a multi spectrum de-wormer for large dogs. 

Treating intestinal worms with Kiwof Plus XL

Kiwof Plus XL Easy Chews 175/504/524 contains a combination of three anthelmintic drugs that are used as a multi spectrum de-wormer for large dogs.  Kiwof Plus XL Easy Chews are effective in the control of all common gastrointestinal worms These include the roundworms (ascarids) Toxicara canis and Toxascaris leonine; the hookworms Ancylostoma caninum and Uncinaria stenocephala; and the whipworm Trichuris vulpis.  They are also effective against intestinal tapeworms (cestodes), including Dipylidium caninum, Taenia taeniaformis, Echinococcus granulosus and Echincoccus multilocularis, and for removal and control of the hyatid cyst, which is the larval form of the tapeworm.  Praziquantel in Kiwof Plus XL Easy Chews is an anthelmintic that is effective against intestinal tapeworms (cestodes) and works by interfering with the tapeworm’s ability to protect itself against its host, causing the tapeworm to lose resistance to digestion by the host digestive enzymes.  The tapeworm becomes disintegrated and is then removed by the host’s immune system, which destroys the tapeworm before it can be passed out in stools.  Pyrantel in Kiwof Plus XL Easy Chews is a depolarising neuromuscular blocking agent that is effective against roundworms and hookworms that attach to the wall of the host’s intestine by small teeth or suckers.  It works by blocking nerve transmission causing sudden muscular contraction followed by paralysis.  This causes the worm to lose its grip on the intestine wall and fall off; it then becomes paralysed and dies and is passed out in the stools.  Febantel in Kiwof Plus XL Easy Chews is inactive but is converted to fenbendazole a benzimidazole anthelmintic, which has a broad spectrum action.  Fenbendazole works by binding to tubulin in the worm cells, a structural protein of microtubules, and this blocks glucose uptake, which depletes energy stores and eventually paralyses the parasite, which then dies.  Although these drugs are effective against parasitic worms in the intestine, they are not well absorbed into the blood of the host and therefore, have minimal side effects. 

What are the side effects of Kiwof Plus XL?

The most commonly reported side effects when taking Kiwof Plus XL include vomiting, diarrhoea and lethargy. 

When should Kiwof Plus XL not be used?

You should not give Kiwof Plus XL Easy Chew tablets 175/504/524 if your dog:

• is allergic to praziquantel, pyrantel pamoate, febantel or any ingredients in Kiwof Plus XL
• is pregnant, without discussion with your veterinarian
• is taking a piperazine deworming medication
• is still a puppy

How should Kiwof Plus XL be used?

You should give your dog one dose of Kiwof Plus XL Easy Chew tablets directly by hand or added to their food, and no starvation is needed before or after treatment. You should repeat the treatment once every 3 months for as long as recommended by your veterinarian professional, to prevent recurrence of infection.  If your dog has a heavy roundworm infestation you can give a repeat dose after 14 days. 

The dose you give should depend on your dog’s body weight.  Each treatment, which may be up to 2 tablets, should be given as a single dose.

• Up to 17.5kg (38.5lb)                       half a tablet
• 17.5-35kg (38.5-77lb)                       one tablet
• 35-52.5kg (77-115.7lb)                     one and a half tablets
• 52.5-70kg (115.7-154.3lb)                 two tablets

How long should you give Kiwof Plus XL?

You should give your dog the appropriate dose for their body weight of Kiwof Plus XL Easy Chew tablets for as long as recommended by your veterinarian professional, to prevent recurrence of infection. 

Missed dose of Kiwof Plus XL

If you miss a dose of Kiwof Plus XL give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Kiwof Plus XL be stored?

You should store your Kiwof Plus XL XL below 25°C in a cool dry place and protect from light.