Nilstat Oral Drops (Nystatin)

Nilstat Oral Drops general information

What is Nilstat Oral Drops used for?

Nilstat Oral Drops are used to treat infections of the mouth and oral cavity caused by the yeast-like fungus Candida albicans. Infection with Candida (candidiasis) is also known as oral thrush and appears as patches of creamy/white spots in the mouth, usually the tongue or cheeks, but can spread to the gums and back of the throat. The infection can cause discomfort and bleed if disturbed such as when brushing your teeth. Candida is normally present in the mouth in small amounts and is kept from spreading by other microorganisms. However, if Candida grows unchecked and increases in numbers sufficient to tip the healthy balance between yeast and bacteria, this can cause infection. Some conditions like diabetes, impaired immune system, such as those imunocompromised by HIV infection can disturb this balance; also some medications like antibiotics and corticosteroids. Wearing ill-fitting dentures can also increase the risk of Candida infection. Nilstat Oral Drops are used as a topical treatment to kill the Candida yeast that causes infection in the mouth, relieving symptoms and preventing spread of infection.

How does Nilstat Oral Drops work?

Nilstat Oral Drops contain nystatin, an antifungal that works by binding to ergosterol, an important component of fungal cell membrane that is not found in animal cells. This weakens the fungal cell membrane, causing a change in permeability and allowing the cell contents to leak out, which kills the fungus, preventing the infection from spreading and relieving symptoms caused by the infection. Nilstat Oral Drops do not absorb into the blood in sufficient amounts to be effective anywhere else in the body.

What does Nilstat Oral Drops contain?

Nilstat Oral Drops contain the active ingredient nystatin (100,000 units/mL), which is an antifungal used to treat Intestinal candidiasis. They also contain propyl hydroxybenzoate, sucrose, polysorbate 80, sodium calciumedetate, methyl hydroxybenzoate, purified water, bentonite, quinoline yellow CI 47005, cherry flavour F-1242.

Treating oral thrush with Nilstat Oral Drops

Nilstat Oral Drops contain nystatin, an antifungal used to treat infections of the mouth and oral cavity caused by the yeast-like fungus Candida albicans, also known as oral thrush. Candida is normally present in the mouth in small amounts and is kept from spreading by a healthy balance between yeast and bacteria. However, some conditions like diabetes and impaired immune system, such as those imunocompromised by HIV infection can disturb this balance; also some medications like antibiotics and corticosteroids. This allows Candida to grow unchecked and result in an infection, which appears as patches of creamy/white spots in the mouth, usually the tongue or cheeks, but can spread to the gums and back of the throat. Wearing ill-fitting dentures can also increase the risk of Candida infection. Nilstat Oral Drops work by binding to ergosterol, an important component of fungal cell membrane that is not found in animal cells. This weakens the fungal cell membrane, causing a change in permeability and allowing the cell contents to leak out, which kills the fungus, preventing the infection from spreading and relieving symptoms caused by the infection, including discomfort and bleeding.

What are the side effects of Nilstat Oral Drops?

The most commonly reported side effects when taking Nilstat Oral Drops are gastrointestinal distress including diarrhoea, nausea and vomiting.

When should Nilstat Oral Drops not be used?

You should not use Nilstat Oral Drops if you:

• are allergic to nystatin or any ingredients in Nilstat Oral Drops
• are pregnant or are breastfeeding, without discussion with your doctor

How should Nilstat Oral Drops be taken?

You should take your Nilstat Oral Drops using the syringe provided four times daily. Shake the bottle and then fill the 1mL syringe with Nilstat Oral Drops. Drop the full amount in the syringe into your mouth or under your tongue. Leave in the mouth for as long as possible before swallowing and ensure all areas of the infection are covered. Wash the syringe and repeat after 3 hours. You should continue taking your Nilstat Oral Drops daily until the contents of the bottle have been used up otherwise the infection may not be fully cleared up and may return.

How long should you take Nilstat Oral Drops?

You should continue taking your Nilstat Oral Drops daily until the contents of the bottle have been used up otherwise the infection may not be fully cleared up and may return.

Missed dose of Nilstat Oral Drops

If you miss a dose of Nilstat Oral Drops take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Nilstat Oral Drops be stored?

You should store your Nilstat Oral Drops below 25°C in a cool dry place.